Caspase-1 initiates apoptosis, but not pyroptosis, in the absence of gasdermin D. Kanazawa University. Journal Nature Communications Funder Grants-in-Aid (KAKENHI), Japan Society for the Promotion ...

Apoptosis is the process of controlled cellular “suicide”. Whereas in necrosis cells die due to injury or disease, apoptosis is a natural part of the regulation and development of the body’s ...

A study has found that a cannabis extract can inhibit the growth of melanoma cells and trigger cell death. The next step is pre-clinical trials to investigate whether the extract can be used to ...

Forms of this process have also been documented in single-celled eukaryotes like yeast. Scientists have long wondered about the origins of this process. New research has found that the apoptosis may ...

There are many different triggers of apoptosis, but they all ultimately activate executioners called caspases. Cleaving hundreds of different kinds of proteins within a cell, these enzymes wreak havoc ...

Apoptosis is a genetically programmed, physiological method of cell destruction. A variety of genes are now recognised as positive or negative regulators of this process. Expression of inducible ...

This begins the process of apoptosis. Simultaneously, the protein HRI is activated by cytochrome c, as part of the stress response pathway. HRI in turn causes more ATF4 to be expressed.

Apoptosis, sometimes called "cellular suicide," is a normal, programmed process of cellular self-destruction. Even though it involves cell death, apoptosis serves a healthy and protective role in ...

In the process of apoptosis, the group of proteases called caspases, about 10 species of which are found in humans, function as suicide enzymes. Caspase-1, ...

The temporal gene expression profile during the entire process of apoptosis and cell cycle progression in response to p53 in human ovarian cancer cells was explored with cDNA microarrays ...