Swyer syndrome is a rare disorder that you may not have heard of before. We'll explain just what it is and how it might ...

Helping organize the support group for the intersex community at UCSF, Jeanne Nollman, who has Swyer Syndrome, a disorder in which a person is born without functional gonads (sex glands) and ...

Around 30% of those with Swyer syndrome develop a gonadal tumor called gonadoblastoma, which is typically noncancerous. However, gonadoblastoma can lead to the development of a cancerous tumor ...

Journal References:. Yen-Shan Chen, Joseph D. Racca, Michael A. Weiss. Tenuous Transcriptional Threshold of Human Sex Determination. I. SRY and Swyer Syndrome at the Edge of Ambiguity.

Swyer Syndrome (also known as 46, XY gonadal dysgenesis with female somatic phenotype) occurs in people whose sex chromosomes match most biological males, but who not only appear female, ...

Weiss said analogous mutations can occur in SOX genes, causing a variety of birth defects or diseases. “Swyer mutations provide clues to help us understand a broad range of SOX diseases and may ...

It turns out that the rigid "line in the sand" over which the human sex chromosomes---the Y and X--- go to avoid crossing over is a bit blurrier than previously thought. Contrary to the current ...