It is maintained throughout pregnancy by continuous fusion of trophoblast cells, and disruptions in fusion are associated with considerable adverse health effects including diseases such as ...

The latest findings support the expectation that the combination therapy will become the new SOC in PD-L1-positive TNBC.

ACVR2A downregulation disrupts the TCF7/c-JUN pathway, impairing trophoblast invasion and proliferation in pre-eclampsia, revealing a genetic susceptibility-associated mechanism of placental ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cells change their metabolic profiles in ...

Fetal intrauterine growth restriction, one of the most common outcomes of pregnancy-induced hypertensions, can be caused by placental dysfunction, resulting from deficient trophoblast syncytialization ...

This study provides an in-depth analysis of syncytiotrophoblast (STB) gene expression at the single-nucleus (SN) and single-cell (SC) levels, using both primary human placental tissues and two ...

Department of Obstetrics and Gynecology, The First Affiliated Hospital of Jinan University, Guangzhou, China (H.N., X.W., J.W., Y.W., Y.G., J.W., K.C.Y., X.H., R.L ...

However, the role of Nodal or Cripto-1 in placental development has not been determined. Methods: To better understand the roles of Nodal and Cripto-1 in trophoblast populations, we employed a ...