More than 75% of diagnosed cases are caused by mutations in the MLC1 gene, which encodes a protein located in the membrane of a type of brain cell called astrocyte.

Antibodies against MLC1 also were elevated in samples from people with other inflammatory neurological diseases. In a final set of tests, the researchers injected anti-MLC1 antibodies into mice ...

Researchers from Bonn and Erlangen identify the protein MLC1 as a target antigen in multiple sclerosis (MS); a chronic inflammatory disease of the central nervous system caused by the immune system. B ...

Researchers at the University Hospital Bonn (UKB), the University of Bonn and the FAU Erlangen-Nuremberg identified the membrane protein MLC1 as a potential target antigen in MS.

In the brain section of an MS patient, the neurons are shown in green and the target antigen MLC1 in red. Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system ...

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